A slightly unhinged cop is partnered with a veteran detective trying to maintain a low stress level in his life. Creator: Matthew Miller Stars: Damon Wayans, Clayne Crawford, Keesha Sharp

Follows two couples living under the same roof who struggle to keep their relationships alive while pursuing their individual dreams. Creators: Jay Duplass, Mark Duplass, Steve Zissis Stars: Mark Duplass, Melanie Lynskey, Amanda Peet

An astronaut struggles to learn how she became pregnant while on a thirteen-month-long solo space mission. Creator: Mickey Fisher Stars: Halle Berry, Pierce Gagnon, Grace Gummer

A 200-year-old man works in the New York City Morgue trying to find a key to unlock the curse of his immortality. Creator: Matthew Miller Stars: Ioan Gruffudd, Alana De La Garza, Joel David Moore

A premiere surgeon is blackmailed in a plot to assassinate the president after her family is taken hostage by a rogue federal agent. Creators: Alon Aranya, Jeffrey Nachmanoff, Omri Givon Stars: Toni Collette, Tate Donovan, Rhys Coiro

A drama centered on the personal and professional lives of five surgical interns and their supervisors. Creator: Shonda Rhimes Stars: Ellen Pompeo, Justin Chambers, Chandra Wilson

A white collar criminal agrees to help the FBI catch other white collar criminals using his expertise as an art and securities thief, counterfeiter, and conman. Creators: Jeff Eastin, Travis Romero Stars: Matt Bomer, Tim DeKay, Willie Garson

After a serial killer imitates the plots of his novels, successful mystery novelist Richard "Rick" Castle receives permission from the Mayor of New York City to tag along with an NYPD homicide investigation team for research purposes. Creator: Andrew W. Marlowe Stars: Nathan Fillion, Stana Katic, Susan Sullivan

Half-brothers Lucas and Nathan Scott trade between kinship and rivalry both on the basketball court and in the hearts of their friends in the small, but not so quiet town of Tree Hill, North Carolina. Creator: Mark Schwahn Stars: Chad Michael Murray, James Lafferty, Hilarie Burton

The characters of the original 'Little Britain' and some new characters feature in this comedic exploration of the modern American society from, and starring, British comedians Matt Lucas and David Walliams. Stars: Matt Lucas, David Walliams, Tom Baker

Four friends in a small coastal town help each other cope with adolescence. Creator: Kevin Williamson Stars: James Van Der Beek, Katie Holmes, Michelle Williams